Approximately 91,000 bottles were dispensed to patients, slightly above the top end of guidance.
Cash and cash equivalents stood at approximately $381 million at quarter end.
Gross margins remained strong and flat at 93%, with gross-to-net discount around 45%, improving sequentially due to reduced patient copays.
R&D expenses increased by $3.3 million primarily due to the TP-04 program and other development activities.
SG&A expenses increased by approximately $44 million year-over-year, driven by sales and marketing costs including DTC advertising and a larger sales force.
Tarsus reported record-breaking Q2 2025 net sales of $102.7 million for XDEMVY, marking the strongest quarter to date.
Adjusted EBITDA grew 9% year-over-year to $105.1 million, while GAAP net income was $12 million compared to $19.6 million in the prior year period.
Collegium Pharmaceuticals reported record quarterly revenue of $188 million, a 29% increase year-over-year, driven by strong performance across its portfolio including Jornay PM and the pain portfolio.
GAAP operating expenses increased 69% year-over-year, and non-GAAP adjusted operating expenses increased 104%, reflecting investments in Jornay commercialization.
Jornay PM generated record quarterly revenues of $32.6 million with prescriptions growing 23% year-over-year.
Operating cash flow was strong at $72.4 million, with $222 million in cash and equivalents at quarter-end.
The pain portfolio achieved record quarterly revenue of $155.4 million, up 7% year-over-year, with all three core pain medicines showing growth.
Acquisitions and foreign currency each contributed approximately 2 points to reported growth.
Adjusted EBITDA margin was 17.6%, flat year-over-year; adjusted net income was $21 million, down $1 million year-over-year.
Adjusted fully diluted EPS was $0.37, down 6% year-over-year, impacted by last year's high-margin COVID business.
Adjusted income from operations was $22 million, up 8% year-over-year, with adjusted operating margin at 12%, down 80 basis points due to COVID and mix headwinds.
Cash position at quarter end was $709 million, up $12 million sequentially, driven by cash flow from operations.
Geographically, North America represented 49% of revenue, Europe 38%, and Asia Pacific and rest of world 13%, with all regions growing mid-teens.
Gross margin was 51.1%, flat year-over-year, with a 3-point mix headwind due to higher resin procurement for OPUS columns.
Repligen reported Q2 2025 revenue of $182 million, a 15% reported increase, 11% organic growth, and 17% organic non-COVID growth.