Arvinas reported $22.4 million in revenue for Q2 2025, down from $76.5 million in Q2 2024, primarily due to the completion of the Novartis License and Asset Agreements by end of 2024 and reduced Pfizer collaboration revenue.
Cash, cash equivalents, and marketable securities totaled approximately $861.2 million at quarter-end, down from $1.04 billion at the end of 2024, with a cash runway extended into the second half of 2028.
General and administrative expenses decreased to $25.3 million from $31.3 million year-over-year, driven by lower personnel and infrastructure costs.
Research and development expenses declined to $68.6 million from $93.7 million, reflecting reprioritization of programs and workforce reduction, partially offset by increased spending on LRRK2 and KRAS programs.
Restructuring costs of $7.4 million were incurred, mainly employee-related, with a $6.4 million reversal of non-cash stock compensation and bonus expenses.